A massive bomb blast claimed by the Islamic State group killed at least 44 people and wounded dozens on Wednesday in the Kurdish-majority Syrian city of Qamishli.
A child was among at least 15 civilians killed in air strikes on an Al-Qaeda-held town in northwestern Syria on Friday, a monitoring group said.
German Chancellor Angela Merkel arrived in a Turkish border province to meet Turkish Prime Minister Ahmet Davutoglu as she works to ease tensions in the deal to tackle the migrant crisis.
Syrian rebels have withdrawn from three villages threatened by Russian strikes in the northern province of Aleppo that borders Turkey, allowing Kurdish fighters to overrun them, a monitor said.