Syrian rebel shelling of a school in government-held western Aleppo killed at least seven children on Sunday morning, the Syrian Observatory for Human Rights monitoring group reported.
At least 27 civilians were killed in regime air strikes, barrel bomb attacks and artillery fire on the rebel-held side of Syria's Aleppo city on Saturday, a monitor said.
The global watchdog tasked with destroying chemical weapons is probing more than 20 reports of the alleged use of toxic arms in Syria since August, its chief told AFP Friday.
Syrian aircraft and artillery pounded rebel-held areas of Aleppo early Friday as Damascus and its ally Moscow intensified a renewed offensive against the rebels.
Syrian air strikes and shelling killed 25 civilians in eastern districts of Aleppo on Thursday, a monitor said, on the third day of a wide-ranging regime assault on rebel-held areas.
Iraqi forces piled pressure on the Islamic State group around Mosul on Thursday, moving closer to cutting off the jihadists' escape route west to Syria and thrusting deeper into the east of the city.
Air strikes battered neighbourhoods around a children's hospital and a blood bank in rebel-held eastern Aleppo on Wednesday in a second day of renewed bombing that has killed at least 32 people, a war monitor, medics and emergency workers said.
Syrian and Russian warplanes bombed rebel-held areas in Aleppo and Idlib province overnight, a monitor said, a day after Moscow announced a fresh offensive against opponents of its Damascus ally.
A flotilla of Russian warships is now in the eastern Mediterranean off the Syrian coast after being sent to reinforce Russia's military in the area, a naval commander said on state television.
German police on Tuesday arrested five men suspected of links to the Islamic State group, who allegedly sought to recruit fighters for the jihadists.
US-backed Kurdish-Arab forces launched an offensive Sunday on the Islamic State group's de facto Syrian capital Raqa, upping pressure on the jihadists who are already battling Iraqi troops in Mosul.